Challenges of scaling-up process for start-ups

Can start-ups finish up?

n this issue of Circulation: Cardiovascular Quality and Outcomes, Xu et al present findings from a search of US patents related to bare-metal coronary stents in an effort to gain insight on how medical device innovation starts and how policies in the United States might help to promote more innovation. 1 Of the 245 patents identified by their search strategy for the years 1984 to 1994, the auth...

Challenges in scaling up a perfusion process

Introduction Perfusion process involves retention of the cells inside the bioreactor while simultaneously removing spent medium and adding fresh medium continuously. The flow rate of addition of fresh and removal of spent medium are generally kept the same (perfusion rate) to maintain the culture volume inside the bioreactor. Cell retention is possible with many devices but the reliability and ...

Bottom-up sales forecasting for Pre-revenue Start-ups

Studying the process of transformation of the start-up to the academic spin off

At todaychr('39')s universities, we are witnessing the emergence of startup companies by the startup teams by student and academic teams; unfortunately, most startups face barriers to success. On the one hand, one of the new topics entering the fourth-generation universities and can be a good target for the future of the startups; the existence of academic spin-offs, centered around scholars...

Streamlining the study start up process

Trial start up is a frenetic time for any trial manager: once a trial has been funded the clock is ticking to get the first participant recruited. There are a number of key activities that need to happen during this stage, so developing standardised processes to help improve effectiveness can make the system more efficient, and help promote best practice. Three of the key processes that have be...